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Indications for Veterinary Use

  • Osteoarthritis
  • Tendon and Ligament tears
  • Bone injuries
  • Muscle tears and strains
  • Cartilage damage
  • Joint injuries
  • Wound Healing
01 (3)

Filter Functionality

  • Simple system
  • “Magic” is in the filter
    • Selectively captures cells of interest (PBMC)
  • Red cells, plasma, and platelets flow through
  • Peripheral Blood Mononuclear cells (PBMC) are captured and subsequently recovered

Macrophage Polarization

  • M1 to M2 polarization is an essential step to wound healing
  • Anti-inflammatory macrophages (M2)  may originate from a new wave of monocytes entering into tissues during the resolution of inflammation
  • PBMC induce M1 to M2 polarization
  • Tissues where macrophages remain activated in the inflammatory M1 phenotype and do not switch into the anti-inflammatory and regenerative M2 phenotype resulting in Chronic Inflammation
  • A new wave of monocytes entering into tissue polarize macrophage in M2 phenotype
02 (1)

MONOcellsVET concentrates PBMC

  • MONOcellsVET preferentially captures and concentrates PBMC
  • Injection of the resulting MONOcellsVET harvest into the injury site induces M2 polarization
  • The harvested MONOcellsVET solution encourages healing
PAX Advanced Therapies

Features of MONOcells VET®

MONOcells VET® is a simple, single use disposable that concentrates PBMC using a unique filter-based technology. As blood flowsthrough the MONOcells VET® system, peripheral blood mononuclear cells (PBMC) are selectively captured on the surface of the filter and then back-flushed into a smaller volume, creating a PBMC concentrate. The MONOcells VET® system has several advantages over other techniques:

No centrifuge or power supply required

• As easy to use in the field as it is in the clinic
• Gentle gravity filtration is easy on cells and platelets, creating a high-quality concentrate that is rich in healing and growth factors
• Cost effective and efficient
• Natural cell therapy to promote healing
• Minimally invasive
• Reduces the risk of adverse reactions by the patient's own blood
• Same day procedure
• Can be used alone or in conjunction with other treatments, depending on the patient's needs

Revolutionizing Regenerative Medicine for Humans & Animals

Pax Advanced Therapies is a pioneering company specializing in the development and distribution of innovative point-of-care autologous cell therapy systems for human and veterinary applications. These systems are designed to address tendon, ligament, muscle, and joint injuries, offering advanced regenerative solutions for human, equine, canine, and other veterinary patients.

MONOVET System Overview

MONOVET is a simple, single use disposable that concentrates PBMCs using a unique filter-based technology. As blood flows through the MONOVET system, peripheral blood mononuclear cells (PBMNC) are selectively captured on the surface of the filter and then back-flushed into a smaller volume, creating a PBMC concentrate.

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PAX Advanced Therapies

Future Expansion to Human Medicine

PAX Advanced Therapies is working to expand its groundbreaking mononuclear cell-based technologies into human medicine. This expansion will further enhance the potential of regenerative treatments and advance the field of cell therapy, offering new possibilities for medical innovations. Connect to learn in detail.

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Paxton Provitera

Meet The Founder Paxton

Paxton Provitera is an experienced biomedical engineer with a background in Physiology and Biophysics. He has spent over 15 years contributing to medical advancements, specializing in research and development.

Our Founder

About the Team

The team at PAX Advanced Therapies is composed of experienced professionals dedicated to advancing the field of cell therapy. We are committed to creating innovative solutions that address both veterinary and human medical needs.

Our Commitments